For families interested in knowing more, contact:
Dr. Caroline Hastings at Children's Hospital Oakland: firstname.lastname@example.org
Dr. Caroline Hastings, a pediatric hematologist/oncologist at UCSF Benioff Children’s Hospital Oakland, discusses her role in treating the first Niemann-Pick Disease Type C (NPC) patients in the U.S. with Trappsol® Cyclo™ and how this grew to a global compassionate-use program for NPC patients, then formal clinical trials at CTD. Dr. Hastings is the Principal Investigator on CTD’s phase I clinical trial, Senior Clinical Advisor on CTD’s phase I/II clinical trial in Europe, and she co-chairs CTD’s Family and Physicians Listening Circle.
Trappsol® Cyclo™ is an experimental treatment for people with Niemann-Pick Disease Type C. It is a proprietary formulation of a ring of sugar molecules known as cyclodextrins. CTD uses hydroxypropyl beta cyclodextrin in its formulation of Trappsol® Cyclo™. Laboratory experiments have shown that Trappsol® Cyclo™ can remove the harmful cholesterol build up from animal cells, and it has been used by NPC patients on a compassionate basis for up to 7 years.
Dr. Benny Liu, a gastroenterologist at Highland Hospital and UCSF Benioff Children’s Hospital, Oakland, California, discusses his groundbreaking research on cyclodextrins as a treatment of Niemann-Pick Disease Type C (NPC), a rare and fatal genetic disease that impacts the brain, lung, liver, spleen, and other organs. Dr. Liu is a member of CTD’s Scientific Advisory Board and a co-Investigator on CTD’s phase I clinical trial using Trappsol® Cyclo™, CTD’s proprietary orphan drug for treatment of NPC.
N. Scott Fine, Chairman and CEO of CTD Holdings, discusses CTD’s evolution from a fine chemicals company to a clinical-stage pharmaceutical company that develops cyclodextrins to treat human disease, particularly the orphan drug Trappsol® Cyclo™ for the treatment of Niemann-Pick Disease Type C, a rare and fatal genetic disease that impacts the brain, lung, liver, spleen, and other organs.
ALACHUA, Fla.--(BUSINESS WIRE)-- CTD Holdings, Inc. (OTCQB: CTDH), a clinical-stage biotechnology company that develops cyclodextrin-based products for the treatment of disease with unmet medical need, today announced that the Company’s Scientific Advisory Board endorsed Alzheimer’s Disease as the company’s next drug development indication. The Scientific Advisory Board met via videoconference on July 17, 2019. The endorsement was made based on the company’s data from an ongoing expanded access program in late-onset Alzheimer’s Disease with Trappsol® Cyclo™ and on data from two ongoing trials using Trappsol® Cyclo™ in Niemann-Pick Disease Type C, a rare genetic disease which may also lead to cognitive decline. The expanded access program in late-onset Alzheimer’s Disease is now in its second year. CTD’s Niemann-Pick Disease Type C trials and the expanded access program in Alzheimer’s are based on intravenous administration of the drug.
CTD Chairman and CEO N. Scott Fine said, “CTD is grateful to the Scientific Advisory Board for its insights and its work. We will move forward to build and launch a clinical trial in Alzheimer’s Disease.”
The Scientific Advisory Board is led by two Co-Chairs: Rita Colwell, PhD, Distinguished University Professor both at the University of Maryland at College Park and at Johns Hopkins University Bloomberg School of Public Health, and former Director of the National Science Foundation, and Sharon Hrynkow, PhD, CTD’s Chief Scientific Officer and Senior Vice President for Medical Affairs.
Scientific Advisory Board members are:
M. Flint Beal, MD, University Professor of Neurology and Neuroscience in the Department of Neurology and Neuroscience at the Weill Medical College of Cornell University - New York Presbyterian Hospital;
Caroline Hastings, MD, Pediatric Hematologist/Oncologist and senior clinician-scientist and educator at the UCSF Benioff Children’s Hospital, Oakland CA; and
Benny Liu, MD, Associate Division Chief of Gastroenterology at Highland Hospital in Oakland, CA and an Assistant Clinical Professor at the University of California, San Francisco (UCSF).
The Scientific Advisory Board plans to meet in late 2019 to consider additional future drug development indications.
About CTD Holdings:
CTD Holdings, Inc. is a clinical-stage biotechnology company that develops cyclodextrin-based products for the treatment of disease. The company’s Trappsol® Cyclo™, an orphan drug designated product in the United States and Europe, is used to treat Niemann-Pick Disease Type C, a rare and fatal genetic disease, on a compassionate use basis as well as in three ongoing formal clinical trials (Clinical Trials.gov NCT02939547, NCT02912793 and NCT03893071). Additional indications for the active ingredient in Trappsol® Cyclo™ are in development. For additional information, visit the company’s website: www.ctd-holdings.com
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Source: CTD Holdings, Inc.